Epidemiology-Calibrated Differentials

WHO GHO 2022 prevalence data · Bayesian prior weighting by region

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How it works

Standard differential diagnosis lists rank conditions by symptom frequency alone — the same list whether you're in Lagos or London. This tool calibrates that list using WHO GHO 2022 incidence data for your selected region.

Posterior ∝ P(symptoms | disease) × P(disease in region)

Malaria ranks #1 for "fever + rigors" in Africa because its local incidence of 23,000/100k dwarfs its European rate of 2/100k — a 10,000× difference that completely reshapes the differential.